¿Cuál es el fundamento de las terapias basadas en la utilización de células t modificadas (car- t-cells)?

Authors

  • Aída E. Sterin Prync Profesora Titular de Biotecnología, Carrera de Bioquímica. Departamento de Bioquímica Aplicada. Instituto Universitario del Hospital Italiano

DOI:

https://doi.org/10.51987/Rev.Hosp.Ital.B.Aires.v38i3.569

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References

Billingham RE, Brent L, Medawar PB. Quantitative Studies on Tissue Transplantation Immunity. II. The Origin, Strength and Duration of Actively and Adoptively Acquired Immunity. Proc R Soc London. 1954; 143(910):58-80. DOI: https://doi.org/10.1098/rspb.1954.0054

Smyth MJ. Multiple approaches to immunotherapy - the new pillar of cancer treatment. Immunol Cell Biol. 2017; 95(4):323-324. DOI: https://doi.org/10.1038/icb.2017.9

Maude SL, Frey N, Shaw PA, et al. Chimeric antigen receptor T cells for sustained remissions in leukemia. N Engl J Med. 2014; 371(16):1507–17. DOI: https://doi.org/10.1056/NEJMoa1407222

Brentjens RJ, Davila ML, Riviere I, et al. D19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia. Sci Transl Med. 2013; 5(177):177ra38. DOI: https://doi.org/10.1126/scitranslmed.3005930

Tran E, Longo DL, Urba WJ, et al. A Milestone for CAR T Cells. N Engl J Med 2017; 377:2593-2596 DOI: https://doi.org/10.1056/NEJMe1714680

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Published

2018-09-30

How to Cite

1.
Sterin Prync AE. ¿Cuál es el fundamento de las terapias basadas en la utilización de células t modificadas (car- t-cells)? Rev Hosp Ital B.Aires [Internet]. 2018 Sep. 30 [cited 2026 Aug. 21];38(3):119-21. Available from: https://ojs.hospitalitaliano.org.ar/index.php/revistahi/article/view/569