Male genital infection by human papiloma virus

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Alejandro Silva Garretón
Milena Mayer
Omar Layus
Gastón Rey Valzacchi
Guillermo Gueglio

Abstract

Human papiloma virus (HPV) is one of the most common sexual transmitted diseases. It can affect the male genitalia, as well as the perianal and anal regions and multiple areas of the head and neck and otorhinolaryngological structures, as benign lesiones or as a promoter of malignant lesions. Benign male genitalia lesions are characterized mainly by verrucous lesions, although flat atypical lesions can be found, as well as the abscence of macroscopic visible lesions that in some cases can become evident using the acetic acid test. Lesion biopsy, its histological evaluation, and the determination of the existence and type of virus using PCR (Polymerase Chain Reaction) can confirm the diagnosis. In some cases is necessary to do a cistoscopy to diagnose intraurethral and vesical lesions. Proposed treatments are varied and with a wide range of efficacy, from topications to electro or cryosurgery, and the use of laser technology. Sexual education and the use of sexual protection are essential in prevention. In the last 10 years the use of VPH vaccine in girls was widely spread, in order to decrease the incidence of high grade lesions and cervix cancer. Its indication in male patients is less clear and not yet consented among specialists

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Published: 2016-12-30
Keywords:
Human papilloma virus, penoscopy, holmium laser, Gardasil, Cervarix

Article Details

Section

Review

How to Cite

1.
Silva Garretón A, Mayer M, Layus O, Rey Valzacchi G, Gueglio G. Male genital infection by human papiloma virus. Rev Hosp Ital B.Aires [Internet]. 2016 Dec. 30 [cited 2026 Jul. 31];36(4):143-9. Available from: https://ojs.hospitalitaliano.org.ar/index.php/revistahi/article/view/637

References

Arbyn M, Bosch X, Cuzick J, y col. IARC Monographs programme on the evaluation of carcinogenic risks to humans. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. 2007;90:9-31.

Barrasso R. Latent and subclinical HPV external anogenital infection. Clin Dermatol. 1997;15(3):349-53.

Bleeker MC, Snijders PF, Voorhorst FJ, y col. Flat penile lesions: the infectious "invisible" link in the transmission of human papillomavirus. Int J Cancer. 2006;119(11):2505-12.

Greer CE, Wheeler CM, Ladner MB, y col. Human papillomavirus (HPV) type distribution and serological response to HPV type 6 virus-like particles in patients with genital warts. J Clin Microbiol. 1995;33(8):2058-63.

Dunne EF, Nielson CM, Stone KM, y col. Prevalence of HPV infection among men: A systematic review of the literature. J Infect Dis. 2006;194(8):1044-57.

Ciapponi A, Bardach A, Glujovsky D, y col. Type-specific HPV prevalence in cervical cancer and high-grade lesions in Latin America and the Caribbean: systematic review and meta-analysis. PLoS One. 2011;6(10):e25493.

Muñoz N, Castellsagué X, de González AB, y col. Chapter 1: HPV in the etiology of human cancer. Vaccine. 2006;24 Suppl 3:S3/1-10.

Laprise C, Trottier H, Monnier P, y col. Prevalence of human papillomaviruses in semen: a systematic review and meta-analysis. Hum Reprod. 2014;29(4):640-51.

Garolla A, Lenzi A, Palù G, y col. Human papillomavirus sperm infection and assisted reproduction: a dangerous hazard with a possible safe solution. Hum Reprod. 2012;27(4):967-73.

Wikström A, Hedblad MA, Johansson B, et al. The acetic acid test in evaluation of subclinical genital papillomavirus infection: a comparative study on penoscopy, histopathology, virology and scanning electron microscopy findings. Genitourin Med. 1992;68(2):90-9.

Weaver BA, Feng Q, Holmes KK, y col. Evaluation of genital sites and sampling techniques for detection of human papillomavirus DNA in men. J Infect Dis. 2004;189(4):677-85.

Rothman I, Berger RE, Kiviat N, y col. Urethral meatal warts in men: results of urethroscopy and biopsy. J Urol. 1994;151(4):875-7.

Bleeker MC, Berkhof J, Hogewoning CJ, y col. HPV type concordance in sexual couples determines the effect of condoms on regression of flat penile lesions. Br J Cancer. 2005;92(8):1388-92.

Wikström A, von Krogh G. Efficacy of surgical and/or podophyllotoxin treatment against flat acetowhite penile human papillomavirus associated lesions. Int J STD AIDS. 1998;9(9):537-42.

Concha R M. [Diagnosis and treatment of human papilloma virus]. Rev Chilena Infectol. 2007;24(3):209-14.

Gammon DC, Reed KA, Patel M, y col. Intraurethral fluorouracil and lidocaine for intraurethral condyloma acuminata. Am J Health Syst Pharm. 2008;65(19):1830-3.

Chrisofos M, Skolarikos A, Lazaris A, y col. HPV 16/18-associated condyloma acuminatum of the urinary bladder: first international report and review of literature. Int J STD AIDS. 2004;15(12):836-8.

Hermann TR, Liatsikos E, Nagele U, et al. Actualización de directrices sobre láseres y tecnologías. European Association of Urology. 2011;1639-97.

Azizjalali M, Ghaffarpour G, Mousavifard B. CO(2) Laser therapy versus cryotherapy in treatment of genital warts; a Randomized Controlled Trial (RCT). Iran J Microbiol. 2012;4(4):187-90.

de Lima MM Jr, de Lima MM, Granja F. Treatment of genital lesions with diode laser vaporization. BMC Urol. 2015;15:39.

Yang CJ, Liu SX, Liu JB, y col. Holmium laser treatment of genital warts: an observational study of 1500 cases. Acta Derm Venereol. 2008;88(2):136-8.

Ge CG, Jiang J, Jiang Q, y col. Holmium: YAG laser ablation combined intraurethral fluorouracil perfusion as treatment option for intraurethral Condyloma acuminata in men. Minerva Urol Nefrol. 2014;66(1):77-81.

Larke N, Thomas SL, Dos Santos Silva I, y col. Male circumcision and human papillomavirus infection in men: a systematic review and meta-analysis. J Infect Dis. 2011;204(9):1375-90.

Giuliano AR, Palefsky JM, Goldstone S, y col. Efficacy of quadrivalent HPV vaccine against HPV Infection and disease in males. N Engl J Med. 2011;364(5):401-11. Erratum in: N Engl J Med. 2011;364(15):1481.

Petrosky E, Bocchini JA Jr, Hariri S, y col. Use of 9-valent human papillomavirus (HPV) vaccine: updated HPV vaccination recommendations of the advisory committee on immunization practices. MMWR Morb Mortal Wkly Rep. 2015;64(11):300-4.

Chow EP, Machalek DA, Tabrizi SN, y col. Quadrivalent vaccine-targeted human papillomavirus genotypes in heterosexual men after the Australian female human papillomavirus vaccination programme: a retrospective observational study. Lancet Infect Dis. 2017;17(1):68-77.

Schmeler KM, Sturgis EM. Expanding the benefits of HPV vaccination to boys and men. Lancet. 2016;387(10030):1798-9.

López Diez E, Pérez S, Iñarrea A, y col. Prevalence and concordance of high-risk papillomavirus infection in male sexual partners of women diagnosed with high grade cervical lesions. Enferm Infecc Microbiol Clin. 2016 Mar 19. pii:S0213-005X(16)00084-7.

Lenzi A, Mirone V, Gentile V, y col. Rome Consensus Conference - statement; human papilloma virus diseases in males. BMC Public Health. 2013;13:117.

Ministerio de Salud de la República Argentina. Vacuna contra el Virus del Papiloma Humano (VPH): Lineamientos Técnicos y Manual del Vacunador 2011:5-50.

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