18-fluorocholine PET/CT in hyperparathyroidism: When to use it?

Main Article Content

Luis A. Boccalatte
Rocío C. Bruballa

Abstract

Identifying parathyroid glands correctly before a procedure is essential to perform minimally invasive surgery. First-line tests with discordant or negative results underscore the need for more accurate imaging tests. After a systematic review, we found that PET/CT with 18F-fluorocholine is useful as a complementary test.

Downloads

Download data is not yet available.

Article Details

Section

Hospital Italiano in Medline

How to Cite

1.
Boccalatte LA, Bruballa RC. 18-fluorocholine PET/CT in hyperparathyroidism: When to use it?. Rev Hosp Ital B.Aires [Internet]. 2022 Mar. 31 [cited 2026 Apr. 27];42(1):p. 49-50. Available from: https://ojs.hospitalitaliano.org.ar/index.php/revistahi/article/view/148

References

DeLellis RA, Mazzaglia P, Mangray S. Primary hyperparathyroidism: a current perspective. Arch Pathol Lab Med. 2008;132(8):1251-1262. https://doi.org/10.5858/2008-132-1251-PHACP. DOI: https://doi.org/10.5858/2008-132-1251-PHACP

Augustine MM, Bravo PE, Zeiger MA. Surgical treatment of primary hyperparathyroidism. Endocr Pract. 2011;17 Suppl 1:75-82. https://doi.org/10.4158/EP10359.RA. DOI: https://doi.org/10.4158/EP10359.RA

Rodgers SE, Lew JI, Solórzano CC. Primary hyperparathyroidism. Curr Opin Oncol. 2008 Jan;20(1):52-58. https://doi.org/10.1097/CCO.0b013e3282f2838f. DOI: https://doi.org/10.1097/CCO.0b013e3282f2838f

Yu H, Burke CT, Commander CW, eds. Diagnosis and management of endocrine disorders in interventional radiology. Cham: Springer; 2022. https://doi.org/10.1007/978-3-030-87189-5. DOI: https://doi.org/10.1007/978-3-030-87189-5

Neumann DR, Obuchowski NA, Difilippo FP. Preoperative 123I/99mTc-sestamibi subtraction SPECT and SPECT/CT in primary hyperparathyroidism. J Nucl Med. 2008;49(12):2012-2017. https://doi.org/10.2967/jnumed.108.054858. DOI: https://doi.org/10.2967/jnumed.108.054858

Thanseer N, Bhadada SK, Sood A, et al. Comparative effectiveness of ultrasonography, 99mTc-Sestamibi, and 18F-Fluorocholine PET/CT in detecting parathyroid adenomas in patients with primary hyperparathyroidism. Clin Nucl Med. 2017;42(12):e491-e497. https://doi.org/10.1097/RLU.0000000000001845. DOI: https://doi.org/10.1097/RLU.0000000000001845

Politz D, Livingston CD, Victor B, et al. Minimally invasive radio-guided parathyroidectomy in 152 consecutive patients with primary hyperparathyroidism. Endocr Pract. 2006;12(6):630-634. https://doi.org/10.4158/EP.12.6.630 DOI: https://doi.org/10.4158/EP.12.6.630

Quak E, Blanchard D, Houdu B, et al. F18-choline PET/CT guided surgery in primary hyperparathyroidism when ultrasound and MIBI SPECT/CT are negative or inconclusive: the APACH1 study. Eur J Nucl Med Mol Imaging. 2018;45(4):658-666. https://doi.org/10.1007/s00259-017-3911-1. DOI: https://doi.org/10.1007/s00259-017-3911-1

Quak E, Lasne Cardon A, Ciappuccini R, et al. Upfront F18-choline PET/CT versus Tc99m-sestaMIBI SPECT/CT guided surgery in primary hyperparathyroidism: the randomized phase III diagnostic trial APACH2. BMC Endocr Disord. 2021;21(1):3. https://doi.org/10.1186/s12902-020-00667-5. DOI: https://doi.org/10.1186/s12902-020-00667-5