Arterial wound Resolution with Follicular Unit Skin Graft: A Case Report
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Chronic ulcers significantly impact patients' quality of life and impose high costs on the healthcare system. A comprehensive therapeutic approach accounting for the diagnosis and wound characteristics is essential for each healing phase. We recommend applying graft techniques during epithelialization to accelerate repair, improve scar tissue quality, and address pain. The technique of autografting using punch follicular units obtained from the scalp is presented as an accepted strategy for repairing chronic wounds. This case study involves a 79-year-old patient with multiple comorbidities and a large arterial ulcer. After controlling the underlying condition and achieving an optimal wound bed, the autograft with follicular units resulted in complete healing within four months.
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Baquerizo Nole KL, Kirsner RS. Hair follicles and their potential in wound healing. Exp Dermatol. 2015;24(2):95-96. https://doi.org/10.1111/exd.12607. DOI: https://doi.org/10.1111/exd.12607
Budamakuntla L, Loganathan E, Sarvajnamurthy SA, et al. Follicular unit grafting in chronic nonhealing leg ulcers: a clinical study. J Cutan Aesthet Surg. 2017;10(4):200-206. https://doi.org/10.4103/JCAS.JCAS_38_17. DOI: https://doi.org/10.4103/JCAS.JCAS_38_17
Martínez Martínez ML, Escario Travesedo E, Jiménez Acosta F. Hair-follicle transplant into chronic ulcers: a new graft concept. Actas Dermosifiliogr. 2017;108(6):524-531. https://doi.org/10.1016/j.ad.2017.02.013. DOI: https://doi.org/10.1016/j.adengl.2017.05.016
Agale SV. Chronic leg ulcers: epidemiology, aetiopathogenesis, and management. Ulcers. 2013;2013:413604. http://dx.doi.org/10.1155/2013/413604. DOI: https://doi.org/10.1155/2013/413604
Crawford BS. An unusual skin donor site. Br J Plast Surg. 1964;17:311-333. https://doi.org/10.1016/s0007-1226(64)80049-7. DOI: https://doi.org/10.1016/S0007-1226(64)80049-7
Cheng CC, Tsutsui K, Taguchi T, et al. Hair follicle epidermal stem cells define a niche for tactile sensation. Elife. 2018;7:e38883. https://doi.org/10.7554/eLife.38883. DOI: https://doi.org/10.7554/eLife.38883
Plikus MV, Gay DL, Treffeisen E, et al. Epithelial stem cells and implications for wound repair. Semin Cell Dev Biol. 2012;23(9):946-953. https://doi.org/10.1016/j.semcdb.2012.10.001. DOI: https://doi.org/10.1016/j.semcdb.2012.10.001
Liu JQ, Zhao KB, Feng ZH, et al. Hair follicle units promote re-epithelialization in chronic cutaneous wounds: a clinical case series study. Exp Ther Med. 2015;10(1):25-30. https://doi.org/10.3892/etm.2015.2465. DOI: https://doi.org/10.3892/etm.2015.2465
Martinot V, Mitchell V, Fevrier P, et al. Comparative study of split thickness skin grafts taken from the scalp and thigh in children. Burns. 1994;20(2):146-150. https://doi.org/10.1016/s0305-4179(06)80012-4. DOI: https://doi.org/10.1016/S0305-4179(06)80012-4
Jiménez F, Garde C, Poblet E, et al. A pilot clinical study of hair grafting in chronic leg ulcers. Wound Repair Regen. 2012;20(6):806-814. https://doi.org/10.1111/j.1524-475X.2012.00846.x. DOI: https://doi.org/10.1111/j.1524-475X.2012.00846.x
Martínez ML, Escario E, Poblet E, et al. Hair follicle-containing punch grafts accelerate chronic ulcer healing: a randomized controlled trial. J Am Acad Dermatol. 2016;75(5):1007-1014. https://doi.org/10.1016/j.jaad.2016.02.1161. DOI: https://doi.org/10.1016/j.jaad.2016.02.1161
Jimenez F, Poblet E, Izeta A. Reflections on how wound healing-promoting effects of the hair follicle can be translated into clinical practice. Exp Dermatol. 2015;24(2):91-94. https://doi.org/10.1111/exd.12521. DOI: https://doi.org/10.1111/exd.12521
Belatti A, Bertarini F, Pombo V, et al. Follicular unit grafting in chronic ulcers: a valuable technique for integrated management. An Bras Dermatol. 2024;99(4):568-577. https://doi.org/10.1016/j.abd.2023.08.012. DOI: https://doi.org/10.1016/j.abd.2023.08.012
Schultz GS, Sibbald RG, Falanga V, et al. Wound bed preparation: a systematic approach to wound management. Wound Repair Regen. 2003;11(Suppl 1):S1-S28. https://doi.org/10.1046/j.1524-475x.11.s2.1.x. DOI: https://doi.org/10.1046/j.1524-475X.11.s2.1.x
Leaper DJ, Schultz G, Carville K, et al. Extending the TIME concept: what have we learned in the past 10 years?(*). Int Wound J. 2012;9(Suppl 2):1-19. https://doi.org/10.1111/j.1742-481X.2012.01097.x. DOI: https://doi.org/10.1111/j.1742-481X.2012.01097.x
Moore Z, Dowsett C, Smith G, et al. TIME CDST: an updated tool to address the current challenges in wound care. J Wound Care. 2019;28(3):154-161. https://doi.org/10.12968/jowc.2019.28.3.154. DOI: https://doi.org/10.12968/jowc.2019.28.3.154
Harries RL, Bosanquet DC, Harding KG. Wound bed preparation: TIME for an update. Int Wound J. 2016;13(Suppl 3):8-14. https://doi.org/10.1111/iwj.12662. DOI: https://doi.org/10.1111/iwj.12662