Sarcoidal Granulomatous Panniculitis Associated with Immune Checkpoint Inhibitors: A Rare Immune-Mediated Cutaneous Adverse Event

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Anamá Di Prinzio
Julia Riganti
Ana C. Torre
Luis D. Mazzuoccolo

Abstract

Immune checkpoint inhibitors (ICIs), or checkpoint inhibitors, have been associated with various inflammatory and autoimmune adverse effects, known as immune-related adverse events (irAEs). Among irAEs, dermatological toxicities are the most prevalent, with maculopapular rash, pruritus, and lichenoid and psoriasiform eruptions being the most common.

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Clinical case

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1.
Di Prinzio A, Riganti J, Torre AC, Mazzuoccolo LD. Sarcoidal Granulomatous Panniculitis Associated with Immune Checkpoint Inhibitors: A Rare Immune-Mediated Cutaneous Adverse Event. Rev Hosp Ital B.Aires [Internet]. 2025 Mar. 27 [cited 2026 Apr. 27];45(1):e0000354. Available from: https://ojs.hospitalitaliano.org.ar/index.php/revistahi/article/view/354

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